Amyotrophic Lateral Sclerosis Type 22, also known as amyotrohpic lateral sclerosis 22 with or without frontotemporal dementia, is related to amyotrophic lateral sclerosis 22 with or without frontotemporal dementia and frontotemporal dementia and/or amyotrophic lateral sclerosis 4. An important gene associated with Amyotrophic Lateral Sclerosis Type 22 is TUBA4A (Tubulin Alpha 4a). Affiliated tissues include brain.