Amyotrophic Lateral Sclerosis 22 with or Without Frontotemporal Dementia, also known as als22, is related to amyotrophic lateral sclerosis type 22. An important gene associated with Amyotrophic Lateral Sclerosis 22 with or Without Frontotemporal Dementia is TUBA4A (Tubulin Alpha 4a). Affiliated tissues include spinal cord and brain, and related phenotypes are amyotrophic lateral sclerosis and frontotemporal dementia