Alzheimer Disease 3 (AD3)

Alias:

Alzheimer Disease, Type 3

Ad3

Alzheimer Disease, Type 3, with Spastic Paraparesis and Unusual Plaques

Alzheimer Disease, Familial, 3, with Spastic Paraparesis and Apraxia

Alzheimer's Disease 3

Alzheimer Disease, Familial, 3, with Spastic Paraparesis and Unusual Plaques

Familial Alzheimer Disease 3 with Spastic Paraparesis and Unusual Plaques

Familial Alzheimer Disease 3 with Spastic Paraparesis and Apraxia

Alzheimer Disease, Protection Against, Due to Apoe3-Christchurch

Alzheimer Disease, Type 3, with Spastic Paraparesis and Apraxia

Early-Onset Familial Alzheimer Disease 3

Alzheimer Disease, Familial, Type 3

Alzheimer Disease 3, Early-Onset

Alzheimer Disease 3, Early Onset

Alzheimer Disease, Familial, 3

Alzheimer Disease Familial 3

Familial Alzheimer Disease 3

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基础信息

疾病表征

基因 & 突变

靶点药物

疾病模型

文献报道

阿尔茨海默病3型，也称为阿尔茨海默病3型，与早发型常染色体显性阿尔茨海默病和轻度认知障碍有关，症状包括肌阵挛、癫痫发作和外锥体系运动功能异常。与阿尔茨海默病3型有关的重要基因是PSEN1（前体蛋白1），其相关通路/超级通路包括阿尔茨海默病、miRNA效应和神经科学。在该疾病的背景下，已提到的药物有左乙拉西坦和拉科酰胺。相关组织包括大脑和皮层，相关表型为癫痫发作和失语症。

Related ID：

MALACARDS：ALZ056

OMIM：607822

MESH：D000544