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中文Alexander Disease (ALXDRD)
Alias:
Alexander's Disease
Axd
Alxdrd
Fibrinoid Degeneration of Astrocytes
Leukodystrophy with Rosenthal Fibers
Dysmyelinogenic Leukodystrophy
Demyelinogenic Leukodystrophy
Alexander's Leukodystrophy
Alexander Disease Type Ii
Alexanders Leukodystrophy
Alexander Disease Type I
Alexanders Disease
Axd Type Ii
Axd Type I
Alx
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Alexander病，又名Alexander病，与白质营养不良和多系统萎缩1有关，症状包括肌肉痉挛和癫痫发作。与Alexander病有关的重要基因是GFAP（胶质纤维酸性蛋白），其相关通路/超级通路包括COPI独立的高尔基体至内质网逆行交通和GDNF信号通路。药物甲硝唑已在该疾病的背景下被提及。附属组织包括脊髓和大脑，相关表型为巨脑和智力障碍
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MALACARDS
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