Alpha-Thalassemia (A-THAL)

Alpha-Thalassemia, also known as alpha thalassemia, is related to hemoglobin h disease and alpha thalassemia-intellectual disability syndrome type 1, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Alpha-Thalassemia is HBA2 (Hemoglobin Subunit Alpha 2), and among its related pathways/superpathways are Glucose / Energy Metabolism and Binding and Uptake of Ligands by Scavenger Receptors. The drugs Peginterferon alfa-2b and Metformin have been mentioned in the context of this disorder. Affiliated tissues include spleen and liver, and related phenotypes are microcytic anemia and abnormal hemoglobin