Agnathia-Otocephaly Complex (AGOTC)

Agnathia-Otocephaly Complex, also known as otocephaly, is related to microphthalmia, syndromic 5 and macs syndrome, and has symptoms including respiratory distress An important gene associated with Agnathia-Otocephaly Complex is PRRX1 (Paired Related Homeobox 1), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and Post-translational modification: synthesis of GPI-anchored proteins. Affiliated tissues include eye and trachea, and related phenotypes are agenesis of corpus callosum and narrow mouth