Adult Syndrome, also known as acro-dermato-ungual-lacrimal-tooth syndrome, is related to attention deficit-hyperactivity disorder and alcohol use disorder, and has symptoms including dry skin An important gene associated with Adult Syndrome is TP63 (Tumor Protein P63), and among its related pathways/superpathways are Gene expression (Transcription) and Signal Transduction. The drug D-Leucine has been mentioned in the context of this disorder. Affiliated tissues include skin and breast, and related phenotypes are abnormality of the dentition and abnormality of the nail