Acute Adrenal Insufficiency

Acute Adrenal Insufficiency, also known as addisonian crisis, is related to adrenal insufficiency, congenital, with 46,xy sex reversal, partial or complete and hypoadrenocorticism, familial. An important gene associated with Acute Adrenal Insufficiency is CYP21A2 (Cytochrome P450 Family 21 Subfamily A Member 2), and among its related pathways/superpathways are Metapathway biotransformation Phase I and II and Diseases of glycosylation. The drugs Hydrocortisone and Hydrocortisone acetate have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland and skin, and related phenotypes are primary adrenal insufficiency and decreased circulating cortisol level