Acquired Generalized Lipodystrophy, also known as lawrence syndrome, is related to lipodystrophy, congenital generalized, type 1 and berardinelli-seip congenital lipodystrophy. An important gene associated with Acquired Generalized Lipodystrophy is RETN (Resistin), and among its related pathways/superpathways are IL-9 Signaling Pathways and Glucose / Energy Metabolism. Affiliated tissues include skin and bone, and related phenotypes are generalized lipodystrophy and hyperinsulinemia