Beriberi, also known as thiamine deficiency, is related to dry beriberi and wet beriberi. An important gene associated with Beriberi is TKT (Transketolase), and among its related pathways/superpathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. The drugs Trimethoprim and Metformin have been mentioned in the context of this disorder. Affiliated tissues include heart and kidney, and related phenotypes are renal/urinary system and liver/biliary system