Meningioma, Familial, also known as meningioma, is related to spinal meningioma and intracranial meningioma, and has symptoms including headache and seizures. An important gene associated with Meningioma, Familial is SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily E, Member 1), and among its related pathways/superpathways are Signal Transduction and PI3K-Akt signaling pathway. The drugs Cytarabine and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include brain and spinal cord, and related phenotypes are chromosomal breakage induced by ionizing radiation and increased sensitivity to ionizing radiation