Lynch Syndrome (HNPCC)
Alias:
Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colon Cancer
Hereditary Nonpolyposis Colorectal Carcinoma
Hereditary Nonpolyposis Colorectal Neoplasms
Familial Nonpolyposis Colon Cancer
Hnpcc
Familial Nonpolyposis Colorectal Cancer
Hereditary Non-Polyposis Colorectal Cancer Syndrome
Colorectal Cancer, Hereditary Nonpolyposis, Type 1
Hereditary Nonpolyposis Colorectal Cancer Syndrome
Hereditary Non-Polyposis Colon Cancer Syndrome
Hereditary Defective Mismatch Repair Syndrome
Hereditary Nonpolyposis Colon Cancer Syndrome
Colorectal Neoplasms, Hereditary Nonpolyposis
Hnpcc - Hereditary Nonpolyposis Colon Cancer
Cancer, Colorectal, Nonpolyposis, Hereditary
Hereditary Nonpolyposis Colorectal Neoplasm
Hereditary Non-Polyposis Colorectal Cancer
Hereditary Non-Polyposis Colon Cancer
Colon Cancer, Familial Nonpolyposis
Cancer Family Syndrome
Coca 1
Basic Information
Medical Symptom
Gene & Mutation
Drugs
Disease Model
References
Lynch Syndrome, also known as hereditary nonpolyposis colorectal cancer, is related to lynch syndrome 1 and lynch syndrome 5. An important gene associated with Lynch Syndrome is MLH1 (MutL Homolog 1), and among its related pathways/superpathways are Infectious disease and Prolactin Signaling. The drugs Fluorouracil and Oxaliplatin have been mentioned in the context of this disorder. Affiliated tissues include colon and small intestine, and related phenotypes are constipation and malabsorption
Basic Information
Inheritance
Age Of Onset
Prevalence
Related Gene
Related Models
Reference
MALACARDS
AD
Adult
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12
193
1243
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Gene & Mutation
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MGI
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Comparison
Al agent
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