Limb-Girdle Muscular Dystrophy (LGMD)

Limb-Girdle Muscular Dystrophy(来自ICD-11)
别称:
Lgmd
Muscular Dystrophies, Limb-Girdle
Lgmd - [limb-Girdle Muscular Dystrophy]
Dystrophy, Muscular, Limb-Girdle
Leyden-Mbius Muscular Dystrophy
Limb Girdle Muscular Dystrophy
Myopathic Limb-Girdle Syndrome
Muscular Dystrophy Limb-Girdle
Limb Girdle Muscle Dystrophy
Erb's Muscular Dystrophy
Limb-Girdle Syndrome
Limb-Girdle Myopathy
Limb Girdle
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Limb-Girdle Muscular Dystrophy, also known as lgmd, is related to muscular dystrophy, limb-girdle, autosomal dominant 1 and autosomal recessive limb-girdle muscular dystrophy type 2a. An important gene associated with Limb-Girdle Muscular Dystrophy is CAPN3 (Calpain 3), and among its related pathways/superpathways are Cardiac conduction and DREAM Repression and Dynorphin Expression. The drugs (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium and Lisinopril have been mentioned in the context of this disorder. Affiliated tissues include heart and skeletal muscle, and related phenotypes are muscle and homeostasis/metabolism
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相关ID:
MESH:D049288
ICD11:887807212

基础信息

遗传方式
发病时间
患病率/发病率
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参考文献
MALACARDS
AR
AD
All ages
1-9/100000
81
657
29

疾病表征

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靶点药物

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疾病模型

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MGI
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