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中文人类
IL6 - Interleukin 6
Alias:
CDF
HGF
HSF
BSF2
IL-6
BSF-2
IFNB2
IFN-beta-2
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这个基因编码一种在炎症和B细胞成熟中起作用的细胞因子。此外，编码的蛋白质已被证明是一种能引起自身免疫性疾病或感染患者发热的内源性致热原。这种蛋白质主要在急性和慢性炎症部位产生，在那里它被分泌到血清中，并通过白细胞介素6受体α诱导转录炎症反应。这个基因的功能与多种炎症相关疾病状态有关，包括对糖尿病和系统性幼年风湿性关节炎的敏感性。已发现编码蛋白质的水平在病毒感染，包括COVID-19（由SARS-CoV-2引起的疾病）中升高。[由RefSeq，2020年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IL6 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
