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中文人类
GLP1R - Glucagon Like Peptide 1 Receptor
Alias:
GLP-1
GLP-1R
GLP-1-R
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这个基因编码一个7-跨膜蛋白，作为胰高血糖素样肽1（GLP-1）激素的受体发挥作用，刺激葡萄糖诱导的胰岛素分泌。这个受体在细胞表面发挥作用，响应GLP-1和GLP-1类似物内化，并在导致胰岛素分泌的信号级联中扮演重要角色。它还在动物模型中显示神经保护作用。这个基因的多态性与糖尿病有关。这个蛋白是治疗2型糖尿病和中风的重要药物靶点。这个基因的可变剪接导致多个转录变异体。[由RefSeq，2016年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GLP1R Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
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Residues
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Score
Related Mouse Models
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Name
MGI
Strain of Origin
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Link
References Literature
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Year
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