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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Aurka - aurora kinase A
Alias:
IAK
Ark1
Ayk1
IAK1
Stk6
AIRK1
ARK-1
Aurora-A
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活组蛋白丝氨酸激酶活性并调节泛素蛋白连接酶的结合活性。在几个过程的上游或内部发挥作用,包括微管细胞骨架组织;卵母细胞成熟的正向调节;以及蛋白质定位到中心体。位于轴突丘;微管细胞骨架;和细胞核中。在几个结构中表达,包括消化系统;骨;脑;眼;和生殖泌尿系统。这个基因的人类同源物与结直肠癌;卵巢癌;和子宫癌有关。与人类AURKA(aurora激酶A)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:20878
ENSEMBL:ENSMUSG00000027496
UNIPROT:P97477
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
20878
3
9
14711 bp
44.77
13
22
Aurka Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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