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中文人类
AGTR1 - Angiotensin II Receptor Type 1
Alias:
AT1
AG2S
AT1B
AT1R
ATR1
AT1AR
AT1BR
AT2R1
HAT1R
AGTR1B
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血管紧张素II是一种强大的血管加压激素，也是醛固酮分泌的主要调节剂。它是心血管系统中控制血压和血量的关键效应子。它通过至少两种类型的受体发挥作用。这个基因编码1型受体，被认为调节血管紧张素II的主要心血管效应。这个基因可能在缺血或梗死心肌血流恢复后生成再灌注心律失常中发挥作用。之前认为存在一个相关的基因，标记为AGTR1B；但现在认为人类只有一个1型受体基因。这个基因的可变剪接导致多个转录变异体。[RefSeq，2020年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
AGTR1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
