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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Gabra2 - gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
Alias:
Gabra-2
C630048P16Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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预测能够激活GABA门控的氯离子通道活性;抑制性细胞外配体门控离子通道活性;以及涉及突触后膜电位调节的传递体门控离子通道活性。预测能够对GABA-A受体活性;苯二氮卓受体活性;以及氯离子通道活性做出贡献。参与抑制性突触组装。位于几个细胞组件中,包括树突;抑制性突触;和神经元细胞体。是突触后特化膜的整合成分。在GABA能突触中活跃。在脑和晶状体中表达。这个基因的人类同源物与酒精使用障碍;自闭症障碍;和发育性和癫痫性脑病78有关。与人类的GABRA2(γ-氨基丁酸A受体α2亚单位)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:14395
ENSEMBL:ENSMUSG00000000560
UNIPROT:P26048
Basic Information
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MW (kDa)
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14395
2
10
137458 bp
51.14
15
12
Gabra2 Genetics information (-)
GRCm39
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* This data comes from NCBI.
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