Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
小鼠
Cdk4 - cyclin-dependent kinase 4
Alias:
Crk3
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
使细胞周期蛋白结合活性以及细胞周期蛋白依赖性蛋白丝氨酸/苏氨酸激酶活性得以实现。在几个过程的上游或内部发挥作用,包括细胞对白介素-4的反应;细胞对脂质的反应;以及脂质代谢过程的调控。位于双细胞紧密连接处;细胞质;以及细胞核。是细胞周期蛋白D2-CDK4复合物和转录调节复合物的一部分。在包括消化系统;鳃弓;生殖泌尿系统;神经系统;以及感觉器官在内的几个结构中表达。用于研究1型糖尿病。此基因的人类同源物与几种疾病有关,包括癌(多种类型);家族性黑色素瘤;胶质母细胞瘤;肥胖症;以及2型糖尿病。与人类的CDK4(细胞周期蛋白依赖性激酶4)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12567
ENSEMBL:ENSMUSG00000006728
UNIPROT:P30285
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12567
2
8
3754 bp
33.75
14
15
Cdk4 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Sequence
Comparison
Al agent
Tutorials
Back to top