Albinism, Ocular, Type I, also known as ocular albinism, is related to aland island eye disease and albinism, ocular, with late-onset sensorineural deafness. An important gene associated with Albinism, Ocular, Type I is GPR143 (G Protein-Coupled Receptor 143), and among its related pathways/superpathways are Prader-Willi and Angelman syndrome and GPR143 in melanocytes and retinal pigment epithelium cells. The drug Lutein has been mentioned in the context of this disorder. Affiliated tissues include eye and skin, and related phenotypes are nystagmus and photophobia