Ccdc88c - coiled-coil domain containing 88C

Enables PDZ domain binding activity; identical protein binding activity; and protein self-association. Involved in protein destabilization and regulation of protein phosphorylation. Predicted to be located in cell junction. Predicted to be active in centrosome and cytoplasm. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; long bone; and reproductive system. Human ortholog(s) of this gene implicated in hydrocephalus and spinocerebellar ataxia type 40. Orthologous to human CCDC88C (coiled-coil domain containing 88C). [provided by Alliance of Genome Resources, Apr 2022]