Mouse
Rab7 - RAB7, member RAS oncogene family
Alias:
Rab7a
Predicted to enable several functions, including guanyl ribonucleotide binding activity; retromer complex binding activity; and small GTPase binding activity. Involved in lipophagy. Acts upstream of or within with a positive effect on establishment of vesicle localization. Located in several cellular components, including late endosome membrane; lipid droplet; and phagophore assembly site membrane. Is extrinsic component of lysosome membrane. Is active in lysosome. Is expressed in limb mesenchyme and lung mesenchyme. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B. Orthologous to human RAB7A (RAB7A, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Rab7 Genetics information (-)
GRCm39
Chr 6: 87976088 - 88022252
Sequence Homology
Mouse Gene:
Human Gene:
Rat Gene:
 Gene Length | ||
| Human | Chr 3 | 88616 bp |
| Mouse | Chr 6 | 46165 bp |
| Rat | Chr 4 | 48791 bp |
 Exon Count | ||
| Human | NM_004637.6 | 6 |
| Mouse | NM_009005.3 | 6 |
| Rat | NM_023950.4 | 6 |
 Transcript Length | ||
| Human | NM_004637.6 | 2185 bp |
| Mouse | NM_009005.3 | 2159 bp |
| Rat | NM_023950.4 | 2087 bp |
 homology Sequence Alignment | ||
| Human | NM_004637.6 | 91.3% |
| Mouse | NM_009005.3 | 100% |
| Rat | NM_023950.4 | 97.1% |
 Protein Length | ||
| Human | NP_004628.4 | 207 aa |
| Mouse | NP_033031.2 | 207 aa |
| Rat | NP_076440.1 | 207 aa |
 Protein homology Sequence Alignment | ||
| Human | NP_004628.4 | 100.0% |
| Mouse | NP_033031.2 | 100% |
| Rat | NP_076440.1 | 99.5% |
Transcripts & Proteins
There are 5 transcripts and 5 protein isoforms for Rab7 gene.
Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
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Target
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Numbers
Title
PMID
Journal
Year
IF
22 Results, 10 per Page
1
2
3
