Pde6b - phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
Alias:
r
rd
rd1
Pdeb
rd-1
rd10
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Predicted to enable 3',5'-cyclic-nucleotide phosphodiesterase activity. Involved in entrainment of circadian clock by photoperiod. Acts upstream of or within detection of light stimulus and retina development in camera-type eye. Located in photoreceptor outer segment. Is expressed in esophagus; eye; and male reproductive gland or organ. Used to study congenital stationary night blindness autosomal dominant 2; retinitis pigmentosa; and retinitis pigmentosa 40. Human ortholog(s) of this gene implicated in congenital stationary night blindness autosomal dominant 2 and retinitis pigmentosa 40. Orthologous to human PDE6B (phosphodiesterase 6B). [provided by Alliance of Genome Resources, Apr 2022]