Predicted to enable double-stranded RNA binding activity; identical protein binding activity; and signaling receptor activity. Involved in several processes, including JNK cascade; positive regulation of angiogenesis; and positive regulation of cytokine production. Acts upstream of or within several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of intracellular signal transduction; and regulation of cytokine production. Predicted to be located in cell surface and cytoplasm. Predicted to be integral component of plasma membrane. Is expressed in brain; cerebral cortex; cerebral cortex ventricular layer; forebrain; and submandibular gland primordium. Human ortholog(s) of this gene implicated in several diseases, including hepatitis B; hepatitis C; human immunodeficiency virus infectious disease; liver cirrhosis; and type 1 diabetes mellitus. Orthologous to human TLR3 (toll like receptor 3). [provided by Alliance of Genome Resources, Apr 2022]