Atf6b - activating transcription factor 6 beta

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to contribute to DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in endoplasmic reticulum unfolded protein response; negative regulation of ATF6-mediated unfolded protein response; and positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress. Predicted to act upstream of or within response to unfolded protein. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of RNA polymerase II transcription regulator complex and protein-DNA complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human ATF6B (activating transcription factor 6 beta). [provided by Alliance of Genome Resources, Apr 2022]