Enables ubiquitin protein ligase activity. Involved in protein autoubiquitination. Predicted to be part of RQC complex. Predicted to be active in cytosol. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and thymus. Orthologous to human LTN1 (listerin E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Apr 2022]