Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of protein ubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of proteolysis. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in bladder; female associated reproductive structure; ovary; ureter; and urethra of female. Orthologous to human SPOPL (speckle type BTB/POZ protein like). [provided by Alliance of Genome Resources, Apr 2022]