Gramd2a - GRAM domain containing 2A

Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in endoplasmic reticulum-plasma membrane tethering and regulation of store-operated calcium entry. Predicted to be located in endoplasmic reticulum and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in organelle membrane contact site. Predicted to be extrinsic component of cytoplasmic side of plasma membrane and intrinsic component of endoplasmic reticulum membrane. Is expressed in cerebellum; cerebral cortex; hippocampus; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human GRAMD2A (GRAM domain containing 2A). [provided by Alliance of Genome Resources, Apr 2022]