Predicted to enable solute:proton antiporter activity. Predicted to be involved in cation transport and transmembrane transport. Predicted to act upstream of or within ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including cardiovascular system; central nervous system; gut; male reproductive gland or organ; and respiratory system. Orthologous to human TMCO3 (transmembrane and coiled-coil domains 3). [provided by Alliance of Genome Resources, Apr 2022]