Enables nucleoside-triphosphate diphosphatase activity. Involved in several processes, including basophil activation involved in immune response; negative regulation of mast cell activation involved in immune response; and negative regulation of mast cell proliferation. Located in external side of plasma membrane. Orthologous to human ENPP3 (ectonucleotide pyrophosphatase/phosphodiesterase 3). [provided by Alliance of Genome Resources, Apr 2022]