Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; and calmodulin-dependent cyclic-nucleotide phosphodiesterase activity. Acts upstream of or within several processes, including response to amphetamine; serotonin metabolic process; and visual learning. Predicted to be located in cytoplasm. Predicted to be active in neuronal cell body. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Orthologous to human PDE1B (phosphodiesterase 1B). [provided by Alliance of Genome Resources, Apr 2022]