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中文小鼠
Furin - furin (paired basic amino acid cleaving enzyme)
Alias:
Fur
PACE
SPC1
Pcsk3
9130404I01Rik
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这个基因编码一种依赖于钙的丝氨酸内蛋白酶，它可以蛋白水解激活穿过分泌途径的不同前蛋白底物。编码的蛋白质在蛋白水解自激活过程中，其N端前肽被切割以生成成熟蛋白质。缺乏编码蛋白质的小鼠在胚胎阶段死亡，并显示动力不足，心脏腹侧闭合缺陷，轴向旋转缺陷和卵黄囊血管系统的异常。可变剪接导致多个转录子变异。[由RefSeq，2015年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Furin Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
