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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Dsg4 - desmoglein 4
Alias:
lah
CDHF13
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个钙粘蛋白家族的成员,该成员形成整联蛋白复合物的重要组成部分,该复合物参与细胞粘附、细胞骨架组织、细胞分类和细胞信号传导。这个基因在基底层以上的表皮和毛囊中表达。编码的前原蛋白经历蛋白水解处理以产生成熟的、功能性的蛋白质。这个基因中的一些特定突变负责小鼠的柳叶状毛发表型。这个基因位于染色体18上一个粘附钙粘蛋白基因簇中。[RefSeq,2016年2月提供]
Related ID:
NCBI:16769
ENSEMBL:ENSMUSG00000001804
UNIPROT:Q7TMD7
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
16769
1
16
36958 bp
114.45
8
2
Dsg4 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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