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中文小鼠
Hic1 - hypermethylated in cancer 1
Alias:
HIC-1
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预测能够使DNA结合的转录抑制活性、RNA聚合酶II特异性的；RNA聚合酶II顺式调控区域序列特异性的DNA结合活性；以及组蛋白脱乙酰酶结合活性。参与DNA损伤响应的内在凋亡信号通路；负调控RNA聚合酶II的转录；以及正调控DNA损伤响应，p53类介导物的信号传导。位于染色质中。在包括消化系统、胚胎间充质、生殖泌尿系统、免疫系统和滋养外胚层在内的几个结构中表达。用于研究Miller-Dieker脑回状畸形综合征。与人类HIC1(HIC ZBTB转录抑制子1)正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Hic1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
