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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Cryga - crystallin, gamma A
Alias:
Secc
Cryg-4
DGcry-4
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
三种主要的可溶蛋白家族,即α、β和γ晶状体,在脊椎动物晶状体中普遍表达。这个基因编码γ-晶状体蛋白家族的一员,可能作为眼睛晶状体的结构成分发挥作用。γ-晶状体蛋白是一组高度对称、单体蛋白,通常缺乏连接肽和末端延伸。它们在早期发育后受到差异调节。五个γ-晶状体基因(γ-A到γ-E)以基因簇的形式串联组织在鼠的基因组段中。另一个γ-晶状体基因(γ-F)在相同染色体上距离该簇较远的上游位置被发现。无论是由于衰老还是特定基因的突变,γ-晶状体已经涉及到白内障的形成。[由RefSeq,2008年7月提供]
Related ID:
NCBI:12964
ENSEMBL:ENSMUSG00000044429
UNIPROT:P04345
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12964
1
3
2981 bp
21.15
6
3
Cryga Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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