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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Crmp1 - collapsin response mediator protein 1
Alias:
DRP-1
Ulip3
CRMP-1
Dpysl1
ULIP-3
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种属于collapse响应调节蛋白家族的蛋白质。这个家族由五个同源的胞质磷酸蛋白组成,这些蛋白在发育和成年神经组织中表达,并调节对细胞外信号的响应。这种蛋白质是一种Semaphorin 3A信号分子,可以调节生长锥的崩溃。生长锥在神经元中调节轴突路径。据报道,这种蛋白质代表一类新的微管相关蛋白质。在人类中,这种蛋白质据报道可以抑制癌细胞的侵袭。在小鼠中,这种基因的缺陷可能与空间记忆性能受损有关。可变剪接导致多个转录变异体,这些变异体编码不同的蛋白质异构体。[由RefSeq,2013年1月提供]
Related ID:
NCBI:12933
ENSEMBL:ENSMUSG00000029121
UNIPROT:P97427
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12933
2
14
50106 bp
62.17
7
12
Crmp1 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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