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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Bub1b - BUB1B, mitotic checkpoint serine/threonine kinase
Alias:
BUBR1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能激活蛋白激酶活性。在细胞周期的有丝分裂中期/后期过渡阶段的上游或内部发挥作用,蛋白质定位到染色体,着丝点区域。位于动粒区,是外部动粒的一部分。在包括消化系统、大脑、生殖泌尿系统、皮肤和感觉器官在内的几个结构中表达。用于研究嵌合体多样整倍体综合症1。这个基因的人类同源物与结直肠癌和嵌合体多样整倍体综合症1有关。与人类的BUB1B(BUB1有丝分裂检查点丝氨酸/苏氨酸激酶B)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12236
ENSEMBL:ENSMUSG00000040084
UNIPROT:Q9Z1S0
Basic Information
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Transcripts
Exons
Length
MW (kDa)
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Reference
12236
2
23
43390 bp
118.39
12
13
Bub1b Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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