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中文小鼠
Alox8 - arachidonate 8-lipoxygenase
Alias:
8-LOX
8S-LOX
Alox15b
15-LOX-2
15-LOX-B
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这个基因属于脂氧合酶(LOX)基因家族，其成员编码催化将分子氧添加到多不饱和脂肪酸(PUFA)以产生脂肪酸氢过氧化物。编码的酶优先将花生四烯酸代谢为产生8-羟基二十碳四烯酸(8-HETE)，而亚麻酸的代谢效率较低。这个基因还可以作为肿瘤抑制因子。这个基因位于一个跨越染色体11上大约75千碱基对的相关基因簇中。[由RefSeq，2013年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Alox8 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
