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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Adamts1 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
Alias:
C3-C5
METH1
ADAMTS
METH-1
ADAM-TS1
ADAMTS-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码ADAMTS(整合素和金属蛋白酶)家族的一员,在蛋白水解过程中生成成熟蛋白质产物。这个分泌蛋白质产物在排卵中起着重要作用,可能是通过切割细胞外基质成分Versican。编码的蛋白质可能增强乳腺癌小鼠模型中的肿瘤发生。这个基因的纯合子敲除小鼠表现出增强的围产期致死性,生长和脂肪组织发育受损,雌性排卵受损。[RefSeq, 2015年10月提供]
Related ID:
NCBI:11504
ENSEMBL:ENSMUSG00000022893
UNIPROT:P97857
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11504
1
9
9287 bp
105.80
7
14
Adamts1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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