小鼠

Adam12 - a disintegrin and metallopeptidase domain 12 (meltrin alpha)

Alias:
Mltna
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个整合素和金属蛋白酶(ADAM)家族的成员,该家族在包括细胞信号传导、粘附和迁移等各种生物过程中扮演重要角色。编码的前原原蛋白经历蛋白水解加工,生成具有成熟功能并定位到细胞表面的蛋白质。约三分之一缺乏编码的蛋白质的小鼠在断奶前死亡。在杜氏肌营养不良症的小鼠模型中过表达编码的蛋白质可以通过防止细胞坏死和炎症来减轻肌肉病理。[RefSeq,2016年5月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
23
341899 bp
98.50
3
5

Adam12 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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