CRISPR/Cas9 genome editing technology was used to generate a deletion of all exons of the gene. Western blotting and immunofluorescence staining confirmed the complete absence of protein expression in the testes of homozygous mutant males. (J:345163)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count