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EN
This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with a guide RNA with the spacer sequence CTCCAATCACCAGGTCGAAT and a single-strand oligonucleotide encoding the changes c.2113-2114CC>GT [p.P705A] and c.2116-2117TG>GA [p.C706D], and c.2085C>A to inactivate the PAM sequence and prevent re-cutting of the repaired allele in ENSMUST00000020991 (GRCm39).
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
