Ugt1a1 is located on chromosome 1 of mice. CRISPR/Cas technology was used to design sgRNA; Ugt1a1 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.

Basic Information

Allele
Strain of Origin
Strain MGI ID
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6JCya
Endonuclease-mediated
Intragenic deletion
--
1
6
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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