CRISPR-cas9 mediated recombination inserted loxP sites in introns 7-8 and 9-10. Cre mediated recombination removed the floxed region. Immunoreactivity assays confirmed the absence of expression in olfactory epithelium from homozygous mice. (J:344977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count