CRISPR/Cas9 technology using 5 sgRNA 5-CTCAACTGTGACTTTCCTGA-3 and 3 sgRNA 5'-TTTCTCAAGGGGAAAGACTG-3 was used to delete exons 2-11 in cis with the Gsdma3tm1.1Lty allele. Four founders (F1-9, F1-12, F1-16, and F1-18) were generated. F1-9 and F1-12 contain the same 11007 bp deletion, F1-16 has a 11024 bp deletion, and F1-18 has a 10998 bp deletion. This record represents pooled data from these lines or data where the line number is not specified. (J:335519)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
Intragenic deletion
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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