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CRISPR/Cas9 technology inserted a CAG promoter, a loxP-flanked neomycin/Stop cassette, human TBL1XR1/TP63 fusion cDNA, IRES and EGFP. The TBL1XR1::TP63 rearrangement, in which the breakpoint is in the WD40 repeat domain of TBL1XR1 and right after the transactivation domain of the TP63, is the most common TP63 fusion seen in lymphomas. (J:343472)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
