Log In|Sign Up
EN
The allele was generated using CRISPR/Cas9 endonuclease-mediated genome editing. The targeting vector was designed to replace the mouse huntingtin (Htt) intron 49, on chromosome 5, with a human HTT intron 49 sequence, which contained a putative splicing site to produce an alternative exon (iExon 49). This is Line4. (J:101977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
