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EN
CRISPR/Cas9 technology generated the paracaspase mutation, a TGT to GCG change resulting in a cysteine to alanine change at amino acid 472 (p.C472A) in exon 11, in zygotes carrying the Malt1em1Krad allele. These mice thus carry the p.C472A mutation as well as p.E324A, p.E814A, and p.E803A. (J:333424)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
