Tyrosine codon 845 (TAT) in exon 25 was changed to a stop codon (TAA) (ENSMUSP00000107058:p.Y845*) using an sgRNA (targeting CCTATGAGATGCGAGTCTACGCA) and an ssODN template with CRISPR/Cas9 technology. (J:342762)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count