The transgene contains a 1.5 kb fragment encompassing the human TNFR1 coding DNA sequence, downstream of the 7.5 kb 5-flanking region of the mouse collagen, type VI, alpha 1 promoter, followed by a 2.1 kb human GH1 minigene. The transgenic line carries 2 copies of the transgene. (J:332764)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count